Animefest.CZ is the oldest and largest anime and manga convention in the Czech Republic, organized by a non-profit organization Brno otaku. As the name suggests, the festival takes place in Brno. More than 200 fans visited the first event in 2004 and each following con attracted more people, with over 5500 attendees in 2017.

The festival program offers a mix of contests (e.g. cosplay and AMV), workshops, talks, discussions and, of course, anime screening.